Kazuki Mochizuki Selected Research

Sucrose (Saccharose)

1/2014	Re-feeding rats a high-sucrose diet after 3 days of starvation enhances histone H3 acetylation in transcribed region and expression of jejunal GLUT5 gene.
1/2013	Inhibition of postprandial hyperglycemia by either an insulin-dependent or -independent drug reduces the expression of genes related to inflammation in peripheral leukocytes of OLETF rats.
1/2010	Reduced expression of β2 integrin genes in rat peripheral leukocytes by inhibiting postprandial hyperglycemia.
7/2009	The alpha-glucosidase inhibitor miglitol suppresses postprandial hyperglycaemia and interleukin-1beta and tumour necrosis factor-alpha gene expression in rat peripheral leucocytes induced by intermittent sucrose loading.
10/2007	Effects of miglitol, an alpha-glucosidase inhibitor, on glycaemic status and histopathological changes in islets in non-obese, non-insulin-dependent diabetic Goto-Kakizaki rats.

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Kazuki Mochizuki Research Topics

Disease

21	Insulin Resistance 03/2022 - 08/2007
15	Hyperglycemia 04/2022 - 02/2009
11	Type 2 Diabetes Mellitus (MODY) 04/2022 - 10/2007
8	Inflammation (Inflammations) 01/2022 - 10/2010
6	Metabolic Diseases (Metabolic Disease) 01/2021 - 01/2011
6	Obesity 12/2016 - 08/2007
4	Glucose Intolerance 04/2020 - 12/2009
4	Cardiovascular Diseases (Cardiovascular Disease) 09/2014 - 07/2011
3	Fatty Liver 09/2021 - 01/2014
3	Fibrosis (Cirrhosis) 09/2021 - 10/2007
3	Body Weight (Weight, Body) 01/2019 - 10/2006
2	Neurodevelopmental Disorders 06/2015 - 07/2014
2	Starvation 01/2014 - 10/2006
2	Overweight 01/2013 - 10/2010
1	Infections 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 01/2021
1	Hepatitis C 01/2021
1	Malnutrition (Nutritional Deficiencies) 01/2019
1	Diabetes Mellitus 12/2016
1	Mental Disorders (Mental Disorder) 01/2016
1	Major Depressive Disorder (Major Depressive Disorders) 04/2015
1	Autistic Disorder (Autism) 07/2014

Drug/Important Bio-Agent (IBA)

14	miglitol (Glyset)FDA Link 03/2021 - 10/2007
11	Insulin (Novolin)FDA Link 01/2021 - 10/2008
11	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 10/2008
10	CytokinesIBA 12/2020 - 10/2008
9	Histones (Histone)IBA 03/2022 - 04/2009
9	GlucosidasesIBA 03/2021 - 01/2010
8	Messenger RNA (mRNA)IBA 09/2021 - 10/2006
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2022 - 04/2009
6	Blood Glucose (Blood Sugar)IBA 01/2020 - 10/2007
6	InterleukinsIBA 02/2013 - 10/2010
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2010
5	Sucrose (Saccharose)IBA 01/2014 - 10/2007
5	Triglycerides (Triacylglycerol)IBA 01/2014 - 10/2009
5	AdiponectinIBA 02/2013 - 08/2007
5	Guanosine Triphosphate (GTP)IBA 01/2013 - 01/2011
4	Alanine Transaminase (SGPT)IBA 01/2014 - 01/2011
4	Interleukin-6 (Interleukin 6)IBA 10/2012 - 10/2010
3	Acarbose FDA LinkGeneric 04/2022 - 12/2010
3	Fatty Acids (Saturated Fatty Acids)IBA 03/2022 - 10/2009
3	CarbohydratesIBA 01/2021 - 10/2010
3	anagliptinIBA 12/2016 - 01/2013
3	LipidsIBA 01/2013 - 10/2009
2	Metformin (Glucophage)FDA LinkGeneric 04/2022 - 12/2016
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 06/2015
2	ChromatinIBA 01/2021 - 06/2015
2	Lysine (L-Lysine)FDA Link 01/2021 - 04/2009
2	Antidepressive Agents (Antidepressants)IBA 01/2016 - 04/2015
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 06/2015 - 10/2009
2	voglibose (Basen)IBA 09/2014 - 12/2010
2	Fatty Acid-Binding ProteinsIBA 09/2014 - 11/2010
2	C-Reactive ProteinIBA 01/2013 - 12/2010
2	EnzymesIBA 01/2011 - 02/2009
2	Hemoglobin AIBA 12/2010 - 10/2010
2	Streptozocin (Streptozotocin)FDA Link 01/2010 - 06/2009
2	AlbuminsIBA 10/2009 - 02/2009
2	alpha-AmylasesIBA 10/2009 - 02/2009
2	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 10/2009 - 08/2007
2	Interleukin-1beta (Interleukin 1 beta)IBA 07/2009 - 06/2009
2	Glycoside Hydrolase InhibitorsIBA 07/2009 - 06/2009
1	Hypoglycemic Agents (Hypoglycemics)IBA 04/2022
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2022
1	Transforming Growth Factor beta (TGF-beta)IBA 09/2021
1	Transforming Growth Factors (Transforming Growth Factor)IBA 09/2021
1	PotassiumIBA 09/2021
1	GlucansIBA 09/2021
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	Polycomb Repressive Complex 1IBA 01/2021
1	Subgenomic RNAIBA 01/2021
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 09/2020
1	Folic Acid (Vitamin M)FDA LinkGeneric 04/2020
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 09/2019
1	Cell Adhesion MoleculesIBA 01/2019
1	SolutionsIBA 01/2019
1	Positive Transcriptional Elongation Factor BIBA 01/2017
1	Dipeptidyl-Peptidase IV InhibitorsIBA 12/2016
1	LeptinIBA 12/2016
1	Glucagon-Like Peptide 1 (GLP 1)IBA 12/2016
1	Growth Hormone (Somatotropin)IBA 03/2016
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2016
1	diazonaphthalenedisulfonic acid (NDS)IBA 06/2015
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 06/2015
1	ElementsIBA 06/2015
1	Carrier Proteins (Binding Protein)IBA 06/2015
1	Imipramine (Janimine)FDA LinkGeneric 04/2015
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 04/2015
1	Serotonin (5 Hydroxytryptamine)IBA 04/2015
1	Plasminogen Activators (Plasminogen Activator)IBA 09/2014
1	ChemokinesIBA 09/2014
1	Monocyte Chemoattractant ProteinsIBA 09/2014
1	Biological ProductsIBA 07/2014
1	DNA (Deoxyribonucleic Acid)IBA 07/2014
1	Sitagliptin Phosphate (Januvia)FDA Link 06/2014

Therapy/Procedure

5	Therapeutics 04/2022 - 06/2014
4	Glycemic Control 04/2022 - 11/2011
1	Drug Therapy (Chemotherapy) 03/2021
1	Physical Therapy Modalities (Physical Therapy Technique) 03/2016